>>/212372/
Weigh 1.20g (10mmol) of reaction substrate 1 in a 50ml three-necked flask, add 20ml of absolute ethanol, then add 0.023g (0.3mmol) of thiourea, heat the oil bath to 40°C, stir and dissolve, then add 2.31g of NBS ( 13mmol), stirring to make the reaction proceed, and insoluble substances are generated, the reaction time is controlled to be 20min, the stirring is stopped, left to cool, suction filtered, the filter cake is washed with absolute ethanol, and vacuum-dried to obtain a yellow crude product, the crude product is washed with anhydrous Recrystallized from ethanol to obtain 1.91g white columnar crystal G1, yield 96%, mp48-51℃, 1 H NMR (CDCl 3 , 500MHz) 7.98(m, 1H), 7.61(m, 1H), 7.49(m, 2H) , 4.45(s, 2H).
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